What Does PDRN do for Your Skin?

What Does PDRN do for Your Skin?

When it comes to PDRN, many people may feel unfamiliar with it. But if "salmon water light needle" is mentioned, would everyone feel very familiar with it? Yes, it's the medical aesthetic therapy that was all the rage among South Korean female celebrities a few years ago and was hailed as the "anti-aging wonder". Today, let's get to know this magical skin care ingredient, PDRN.

1. The brief introduction of PDRN

PDRN (polydeoxyribonucleotide) is a specific DNA fragment extracted from the reproductive cells of salmon or the seminal vesicles of salmon, with a base similarity of up to 98% to human DNA

The INCI name of PDRN in cosmetic raw materials is sodium DNA.

Xi'an Season Biotechnology PDRN salmon dna powder specification data sheet as below:

This is the PDRN powder form, if you need liquid form or other specifications powder form, pls feel free to contact us!

2. PDRN Mechanism：

The mechanism of PDRN is to bind to adenosine A2A receptor, activate skin regeneration

Mechanism ability, promote the release of epidermal cell growth factor (EGF) and vascular endo-thelial cytokine (VEGF), and accelerate wound repair and healing.

3. What does PDRN do for your skin?

The PDRN for skin effects mainly as below:

(1) PDRN salmon dna inhibit inflammatory responses and improve skin irritation

Inflammation is closely related to skin sensitivity, instability and skin aging. PDRN has a powerful anti-inflammatory effect and reduces local inflammatory responses by lowering the expression of inflammatory cytokines. In addition, in scar tissue, the number of inflammatory cells was significantly reduced after PDRN treatment. Based on the anti-inflammatory effect of PDRN, it can effectively improve skin irritation symptoms.

(2) PDRN promote wound healing and improve the skin repair process

PDRN plays an active role in wound healing and tissue repair, effectively improving the skin repair process. It not only restores normal cell proliferation but also effectively prevents the development of hypertrophic scars during tissue repair. As an activator of skin cell repair, PDRN is an ideal enhancer for skin wound healing.

(3) PDRN promote collagen regeneration and combat the aging state of the skin

PDRN is a potential anti-aging agent. Research shows that PDRN can promote collagen synthesis, inhibit metalloproteinase and elastase, and play a role in reshaping the extracellular matrix to combat skin aging.

A. Promote the growth of fibroblasts

B. Antioxidant

C. Promote collagen regeneration

(4) PDRN anti-melanin production and slow down skin pigmentation

Melanin production is regulated by melanin production enzymes and melanin production genes. PDRN is a hypopigmented agent that can inhibit the activity of tyrosinase and block the expression of melanin production genes from the source, thereby reducing melanin production

In addition to these effects on the skin, PDRN salmon dna also plays a significant role in clinical treatment.

1. PDRN can shorten the healing time of the donor site in autologous skin transplantation. Local injection of PRP and PDRN plays a certain role in improving the survival rate of composite grafts.

2. For patients with chronic wounds that do not heal, PDRN promotes wound healing by facilitating cell growth, tissue repair and angiogenesis.

For patients with venous ulcers, the combination of PDRN and HA may be the key to accelerating wound repair in patients with lower extremity venous ulcers.

During the treatment of patients with diabetic foot ulcers, pathological observations in the PDRN group showed that compared with the control group, angiogenesis increased and inflammation was significantly improved in the PDRN group. PDRN could promote the healing of Wagner 1 or 2 diabetic foot ulcers.

The use of PDRN and invasive bipolar radiofrequency assisted therapy can significantly improve the efficacy of nasal revision surgery and nasal septoplasty in treating nasal contractile skin, and there are no obvious side effects.

For patients with corneal epithelialization after refractive keratectomy, PDRN promotes corneal epithelial regeneration. patients have good tolerance during the re-epithelialization stage by PDRN eye drops are administered four times a day.

7. For patients with burns and laser vaporization injuries, the use of drugs such as polydeoxynucleotide (PDRN)5mg(POLIDES 5-Farmigea), which have re-epithelialization and anti-complement effects, seems to promote the rapid recovery of the burned or vaporized area while avoiding secondary inflammatory responses.

8. For patients with oral mucositis, within the first week of PDRN treatment, the OM lesion was reduced to grade 2. After starting PDRN spray treatment for 2 to 3 days, the pain was relieved, and all patients completed radiotherapy and chemotherapy without any interference.

9. For patients with lateral epicondylitis (LEE), two weeks after the injection of PDRN, all patients reported significant pain relief. Two weeks after the injection of PDRN, ultrasound examination showed that the vascular hyperplasia of the extensor tendons of the patients had been completely cured.

10. PDRN injection is an effective and safe treatment method for chronic plantar fasciitis.

Above is the brief introductions of the PDRN, if you also wants to know others info of PDRN salmon dna, pls feel free to contact us, we also produce other skin care materials

Hyaluronic acid

Ceramide

Glutathione

Polyglutamic acid

NMN

NR

GHK-cu

AHK-cu

alpha-bisabolol

Resveratrol

If you're looking for the above high quality skin care materials, pls feel free to contact us.

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